By Coach Toria, President of WellFit Health Solutions

What is Uric Acid (UA)?

  • Also known as sodium urate
  • A powerful antioxidant that helps to protect cells from oxidative stress unless levels become excessive
  • The product of the breakdown of purines, or nitrogen compounds
  • Normally excreted in urine unless kidney health is compromised
  • Catalyzed by xanthine oxidase, the enzyme which is responsible for the production of uric acid & free radicals.
  • High uric acid levels in the bloodstream is called hyperuricemia (serum urate concentration: at or above 6.8 mg/dL.)
  • Health conditions may result when the kidneys are unable to properly excrete uric acid
  • More likely to crystallize in cooler extremities, especially the joint of the big toe

What causes high uric acid?

  • Heredity
  • Excess intake of dietary purinehigh fructose corn syrup & sugar
  • Inhibited kidney function, reduced excretion of uric acid
  • Fasting, rapid weight loss or overeating
  • Certain medications (thiazide diuretics may interfere with renal clearance & increase uric acid levels in the blood by)
  • Inadequate production of uricase, the enzyme which oxidizes UA into a soluble compound
  • Alcohol intake
  • Stress
  • Surgery
  • Joint injury
  • Chemotherapy due to cellular breakdown
  • Candida infections & repeated bouts of antibiotics

Who is typically affected?

  •  90% of individuals with gout resulting from high UA are men
  • Men between the ages of 40 & 50 are most commonly afffected
  • 25% of sufferers have a hereditary history

Health complications related to high uric acid

Gout

  • A painful type of arthritis
  • Inflammation & intense immune response
  • Joints look inflamed, hot & sensitive to touch
  • Designated by needle-like crystals of uric acid in joints, capillaries, skin, & other tissues
  • Joint damage may result
  • Kidney stones may occur when the urate crystallizes in the kidney.
  • Occurs in stages from acute to remission to more acute attacks & eventually advanced gout

 Lesch-Nyhan syndrome

  • An extremely rare inherited disorder associated with very high serum uric acid levels
  • Symptoms include: Muscle spasticity, involuntary movement, & cognitive retardation

Cardiovascular disease

  • UA is associated with myocardial ischemia (lack of oxygen to muscle tissue) & myocardial dysfunction (involving impaired peripheral blood flow)
  • High levels of UA are a strong predictor of death from cardiovascular disease, stroke & all causes.
  • Increased risk of high blood pressure especially in black men

Type 2 diabetes: High UA may be a precursor or result

Metabolic syndrome

Uric acid stone formation

Mild cognitive impairment, including loss of mental ability or memory, may occur.

Possible Solutions to Overcome Excess UA

Dietary Guidelines

  • Drink plenty of distilled water so organs can better flush uric acid from the body
  • Eat plenty of raw fruits & vegetables, such as tomatoes & cabbage, that have high water content
  • Eat parsley on a regular basis
  • Drink cherry juice, chamomile tea & celery juice diluted with water
  • Consume blueberries, strawberries & cherries which neutralize UA & are rich in antioxidants
  • Consume a variety of grains, like brown rice, millet & quinoa, starchy & green vegetables, corn, cornbread, seeds & nuts, eggs & dairy products

Foods to avoid

  • Meats, organ meat, processed meats, shellfish, anchovies, mackerel, herring, & sardines
  • Fried foods, roasted nuts & any foods that have been cooked with highly heated oils
  • Meat gravies, broths & consommé
  • Foods which contain yeast such as breads
  • Beer & alcoholic beverages
  • White flour products, like cakes & cookies & other processed foods
  • Mincemeat & sweetbreads
  • Mushrooms & peanuts

Foods to eat in moderation

  •  Asparagus, cauliflower, mushrooms, carrots, rhubarb, potatoes, peas, spinach
  • Legumes: lima beans, kidney beans, lentils, navy beans, soybeans
  • Oatmeal, pickled items, jams & jellies
  • Chicken, turkey, quail
  • Caffeine, sugars, chocolate & sugar-sweetened drinks
  • Carbonated beverages – A study found that men who drank two or more sugar-sweetened beverages a day have an 85% higher chance of developing gout than those who drank them infrequently.

Nutritional Supplements to consider

  • Juice Plus+ Whole Food capsules – provides a full spectrum of phytonutrients from fruits & vegetables; helps reduce oxidative stress, inflammation & free radical damage
  • Vitamin C – reduces UA levels
  • Essential Fatty Acids – helps counter increases in UA
  • Proteolytic enzymes – improves protein digestion
  • B complex – reduces stress & enhances digestion
  • Vitamin E (d-alpha-tocopherol) – Improves circulation
  • Free-form amino acid complex – helps counter increases in UA
  • Kelp or alfalfa – contains minerals & complete protein; reduces UA
  • Micellized Vitamin A – potent antioxidant; helps reduce uric acid
  • MSM (methylsulonyl-methane) – excellent for joint health & all connective tissues; reduces inflammation & relieves pain
  • Boswellia & turmeric are potent anti-inflammatories

Medications:

  • Uricosuric drugs, including  allopurinol, probenecid & sulfinpyrazone, help the kidneys excrete more uric acid
  • NSAIDs (non-steroidal anti-inflammatory drugs), like Indocin,  or corticosteroids are typically given for bouts of inflammation
  • Allopurinol help manage urate levels in people who over produce UA by blocking the conversion of hypoxanthine to xanthine to uric acid
  • Uricase enzymes catabolize UA to a more soluble form which is readily excreted by the kidneys One such drug is Rasburicase however serious side effects can occur.
  • Colchicine alleviates acute attacks of gout, but can cause serious side effects & toxicity
  • Cortisone may be used for relief of gout attacks but puts additional stress on the adrenals

Topical solutions to tame flare-ups from high UA:

  • Pure DMSO (dimethylsulfoxide)
  • Capsicum powder mixed with wintergreen oil (mix until paste forms)

 

Phyllis A. Balch, C. (2006). Prescription for Natural Healing – 4th edition. New York, NY: The Penguin Group.

www.raysahelian.com/uric.html

www.mayoclinic.com/health/high-uric-acid-level/MY00160

www.nlm.nih.gov/medlineplus/ency/article/003476.htm